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I ended up going with Toyo AT3 285/50/22. fits like a glove with zero rubbing. 33.3 x 11.7. the 285/55/22 would have been too much tire at a full inch taller in my opinion. I am currently running 38lbs of air and all seems great.

2024 GX550 Luxury Plus 285/50/22 Toyo Open Country AT3 on oem Lexus 22. Zero rubbing, fits great and dressed wheel up tremendously. 33.3 x 11.7 I looked for others like this for weeks trying to find best size with very few out there on 22s. I hope this post helps others with interest. Before...

@ingogxnito PM.. Trying to figure out is that full stock without trimming? Rubbing like hell? I have lux plus and really want the 285/55s, but worried it is too much tire over the 50.. Any help would be sincerely apprecaited on the details of that truck?